Beltway Beat

FDA Announces Updates to Modernize, Strengthen Pesticide Monitoring Compliance Program

By Food Safety Tech Staff
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May 28, 2026


• Categories: Beltway Beat, Food Labs, Food Manufacturing, Foodservice & Retail

The FDA’s Human Foods Program announced in a press release several key enhancements designed to modernize and strengthen the agency’s monitoring of pesticides in domestic and imported human foods through revisions to Compliance Program 7304.004, last updated in 2011.

According to the press release, these updates strengthen the FDA’s regulatory pesticide residue monitoring program, through which the agency selectively monitors approximately 3,500 domestic and import samples yearly for residues of approximately 780 different pesticides. The FDA also monitors pesticides in human foods through focused surveys and the FDA’s Total Diet Study, and works with states through the Laboratory Flexible Funding Model Program to conduct additional monitoring.

The updated compliance program will focus exclusively on monitoring pesticide residues in foods. To reflect this, the program has been renamed “Pesticides in Human Foods – Domestic and Import.”  The updates streamline the program and clarify specific objectives such as:

• Risk-based Sampling Priorities 
  The updates include a focus on sampling foods highly consumed by infants and children among more than 150 raw agricultural commodities the FDA samples as part of its responsibility to enforce EPA-established tolerances. These procedural enhancements ensure resources are directed toward the areas of greatest potential risk.
• Enhanced Operational Procedures
  Instructions for laboratory, compliance, and enforcement staff have been revised to align with updated FDA procedures. Updates to the laboratory testing methods reflect the transition by FDA regulatory laboratories to a harmonized multi-analyte gas- and liquid-chromatography tandem mass spectrometry method for determination of pesticide residues and elimination of separate, analyte-specific methods, improving throughput and consistency of results. All activities related to industrial chemicals, including dioxins, will now be conducted under their own programs and references in the compliance program will be removed.
• Strengthened Collaboration with Regulatory Partners
  New information has been added that outlines interactions and partnerships with FDA centers, related FDA compliance programs, other federal agencies, and U.S. state and local counterparts, highlighting the FDA’s commitment to a collaborative approach to food safety.

Information on the FDA’s pesticide residue monitoring program, including annual summary reports and the newly released Pesticide Report Data Dashboard, visit FDA’s Pesticides webpage.